The invention relates to immunostimulatory oligonucleotide compositions.
These oligonucleotides comprise an immunostimulatory octanucleotide
sequence. These oligonucleotides can be administered in conjunction with
an immunostimulatory peptide or antigen. Methods for modulating an immune
response upon administration of the oligonucleotide are also disclosed.
In addition, an in vitro screening method to identify oligonucleotides
with immunostimulatory activity is provided.