A globulin-1 regulatory region is shown, a nucleotide sequence of approximately 3 kb which provides improved seed preferred, and particularly embryo preferred expression in plants. Methods of use are also shown in preferentially expressing a heterologous protein to the embryo tissue of a plant. The sequence is particularly useful in expression of heterologous proteins to the embryo of monocotyledonous plants, particularly cereals, and maize.

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> Antibodies to vascular endothelial cell growth factor

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